Reaume, Andrew. G. : rechercher sur Z-Library

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1

Expression analysis of a Notch homologue in the mouse embryo

Andrew G. Reaume, Ronald A. Conlon, Ralph Zirngibl, Terry P. Yamaguchi, Janet Rossant

Journal:

Developmental Biology

Année:

1992

Langue:

english

Fichier:

PDF, 23.07 MB

english, 1992

2

theraTRACE®: a mechanism unbiased in vivo platform for phenotypic screening and drug repositioning

Michael S. Saporito, Andrew G. Reaume

Journal:

Drug Discovery Today: Therapeutic Strategies

Année:

2011

Langue:

english

Fichier:

PDF, 262 KB

english, 2011

3

Is Corporate Venture Capital a Prescription for Success in the Pharmaceutical Industry?

Journal:

The Journal of Private Equity

Année:

2003

Langue:

english

Fichier:

PDF, 145 KB

english, 2003

4

In vivo phenotypic screening: clinical proof of concept for a drug repositioning approach

Ciallella, John R., Reaume, Andrew G.

Journal:

Drug Discovery Today: Technologies

Année:

2017

Langue:

english

Fichier:

PDF, 522 KB

english, 2017

5

High throughput in vivo phenotypic screening for drug repurposing: Discovery of MLR-1023 a novel insulin sensitizer and novel Lyn kinase activator with clinical proof of concept

Lipinski, Christopher A., Reaume, Andrew G.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2020

Langue:

english

Fichier:

PDF, 1009 KB

english, 2020

6

Cu/Zn SOD deficiency potentiates hearing loss and cochlear pathology in aged 129,CD-1 mice

McFadden, Sandra L., Ding, Dalian, Burkard, Robert F., Jiang, Haiyan, Reaume, Andrew G., Flood, Dorothy G., Salvi, Richard J.

Journal:

The Journal of Comparative Neurology

Année:

1999

Langue:

english

Fichier:

PDF, 714 KB

english, 1999

7

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

Reaume, Andrew. G., Elliott, Jeffrey L., Hoffman, Eric K., Kowall, Neil W., Ferrante, Robert J., Siwek, Donald R, Wilcox, Heide M., Flood, Dorothy G., Beal, M. Flint, Brown, Robert H.

Journal:

Nature Genetics

Année:

1996

Fichier:

PDF, 693 KB

1996

8

Effects of over- and under-expression of Cu,Zn-superoxide dismutase on the toxicity of glutamate analogs in transgenic mouse striatum

Paul J Schwartz, Andrew Reaume, Richard Scott, Joseph T Coyle

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 293 KB

english, 1998

9

In vitro photochemical cataract in mice lacking copper-zinc superoxide dismutase

Anders Behndig, Kurt Karlsson, Andrew G Reaume, Marie-Louise Sentman, Stefan L Marklund

Journal:

Free Radical Biology and Medicine

Année:

2001

Langue:

english

Fichier:

PDF, 210 KB

english, 2001

10

Superoxide-Mediated Cytotoxicity in Superoxide Dismutase-Deficient Fetal Fibroblasts

Ting-Ting Huang, Michio Yasunami, Elaine J. Carlson, Anne Marie Gillespie, Andrew G. Reaume, Eric K. Hoffman, Pak H. Chan, Richard W. Scott, Charles J. Epstein

Journal:

Archives of Biochemistry and Biophysics

Année:

1997

Langue:

english

Fichier:

PDF, 5.72 MB

english, 1997

11

Analysis of leukemia inhibitory factor and leukemia inhibitory factor receptor in embryonic and adult zebrafish (Danio rerio)

Patrick C. Hanington, Shunmoogum A. Patten, Laura M. Reaume, Andrew J. Waskiewicz, Miodrag Belosevic, Declan W. Ali

Journal:

Developmental Biology

Année:

2008

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2008

12

Hindlimb Motor Neurons Require Cu/Zn Superoxide Dismutase for Maintenance of Neuromuscular Junctions

Dorothy G. Flood, Andrew G. Reaume, John A. Gruner, Eric K. Hoffman, James D. Hirsch, Yin-Guo Lin, Karen S. Dorfman, Richard W. Scott

Journal:

The American Journal of Pathology

Année:

1999

Langue:

english

Fichier:

PDF, 943 KB

english, 1999

13

Presenilin P264L knock-in mutation: Differential effects on abproduction, amyloid deposition, and neuronal vulnerability

Robert Siman, Andrew G. Reaume, Mary J. Savage, Richard W. Scott, Dorothy G. Flood

Journal:

Neurobiology of Aging

Année:

2000

Langue:

english

Fichier:

PDF, 187 KB

english, 2000

14

FAD mutant PS-1 gene-targeted mice: increased Aβ42 and Aβ deposition without APP overproduction

Dorothy G Flood, Andrew G Reaume, Karen S Dorfman, Yin-Guo Lin, Diane M Lang, Stephen P Trusko, Mary J Savage, Wim G Annaert, Bart De Strooper, Robert Siman, Richard W Scott

Journal:

Neurobiology of Aging

Année:

2002

Langue:

english

Fichier:

PDF, 482 KB

english, 2002

15

Age-related cochlear hair cell loss is enhanced in mice lacking copper/zinc superoxide dismutase

Sandra L McFadden, Dalian Ding, Andrew G Reaume, Dorothy G Flood, Richard J Salvi

Journal:

Neurobiology of Aging

Année:

1999

Langue:

english

Fichier:

PDF, 430 KB

english, 1999

16

Drug repurposing through nonhypothesis driven phenotypic screening

Andrew G. Reaume

Journal:

Drug Discovery Today: Therapeutic Strategies

Année:

2011

Langue:

english

Fichier:

PDF, 90 KB

english, 2011

17

Phenotypes of Mice Lacking Extracellular Superoxide Dismutase and Copper- and Zinc-containing Superoxide Dismutase

Sentman, Marie-Louise, Granström, Micael, Jakobson, Håkan, Reaume, Andrew, Basu, Samar, Marklund, Stefan L.

Journal:

Journal of Biological Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 634 KB

english, 2006

18

Predicting Intracerebral Hemorrhage Growth With the Spot Sign

Dowlatshahi, Dar, Brouwers, H. Bart, Demchuk, Andrew M., Hill, Michael D., Aviv, Richard I., Ufholz, Lee-Anne, Reaume, Michael, Wintermark, Max, Hemphill, J. Claude, Murai, Yasuo, Wang, Yongjun, Zhao,

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 832 KB

english, 2016

19

Role of CuZn superoxide dismutase in regulating lymphocyte apoptosis during sepsis

Freeman, Bradley D., Reaume, Andrew G., Swanson, Paul E., Epstein, Charles J., Carlson, Elaine J., Buchman, Timothy G., Karl, Irene E., Hotchkiss, Richard S.

Journal:

Critical Care Medicine

Année:

2000

Langue:

english

Fichier:

PDF, 2.70 MB

english, 2000

20

Targeted Deletion of the Cytosolic Cu/Zn-Superoxide Dismutase Gene (Sod1) Increases Susceptibility to Noise-Induced Hearing Loss

Ohlemiller, Kevin K., McFadden, Sandra L., Ding, Da-Lian, Flood, Dorothy G., Reaume, Andrew G., Hoffman, Eric K., Scott, Richard W., Wright, James S., Putcha, Girish V., Salvi, Richard J.

Journal:

Audiology & Neuro-Otology

Année:

1999

Langue:

english

Fichier:

PDF, 377 KB

english, 1999

21

Identification of Two Regulatory Elements within the Promoter Region of the Mouse Connexin 43 Gene

Chen, Zhi-Qing, Lefebvre, Diana, Bai, Xiao-Hui, Reaume, Andrew, Rossant, Janet, Lye, Stephen J.

Journal:

Journal of Biological Chemistry

Année:

1995

Fichier:

PDF, 7.33 MB

1995

22

Cellular response of antioxidant metalloproteins in Cu/Zn SOD transgenic mice exposed to hyperoxia

Levy, Mark A., Tsai, Yu-Hwai, Reaume, Andrew, Bray, Tammy M.

Journal:

American journal of physiology. Lung cellular and molecular physiology

Année:

2001

Langue:

english

Fichier:

PDF, 634 KB

english, 2001

23

Reduction of CuZn-Superoxide Dismutase Activity Exacerbates Neuronal Cell Injury and Edema Formation after Transient Focal Cerebral Ischemia

Kondo, Takeo, Reaume, Andrew G., Huang, Ting-Ting, Carlson, Elaine, Murakami, Kensuke, Chen, Sylvia F., Hoffman, Eric K., Scott, Richard W., Epstein, Charles J., Chan, Pak H.

Journal:

Journal of Neuroscience

Année:

1997

Fichier:

PDF, 1.47 MB

1997

24

Turnover of Amyloid Î²-Protein in Mouse Brain and Acute Reduction of Its Level by Phorbol Ester

Savage, Mary J., Trusko, Stephen P., Howland, David S., Pinsker, Leonard R., Mistretta, Suzanne, Reaume, Andrew G., Greenberg, Barry D., Siman, Robert, Scott, Richard W.

Journal:

Journal of Neuroscience

Année:

1998

Fichier:

PDF, 347 KB

1998

25

Presenilin-1 P264L Knock-In Mutation: Differential Effects on AÎ² Production, Amyloid Deposition, and Neuronal Vulnerability

Siman, Robert, Reaume, Andrew G., Savage, Mary J., Trusko, Stephen, Lin, Yin-Guo, Scott, Richard W., Flood, Dorothy G.

Journal:

Journal of Neuroscience

Année:

2000

Fichier:

PDF, 579 KB

2000

26

Prevalence and the predictive performance of the dynamic CT-angiography spot sign in an observational cohort with intracerebral hemorrhage

Dowlatshahi, Dar, Chung, Hee Sahng, Reaume, Michael, Hogan, Matthew J., Blacquiere, Dylan, Stotts, Grant, Shamy, Michel, Momoli, Franco, Aviv, Richard, Demchuk, Andrew M., Chakraborty, Santanu

Journal:

Medicine (Williams & Wilkins)

Année:

2020

Fichier:

PDF, 237 KB

2020